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. 2012 Aug 1;87(2):292–296. doi: 10.4269/ajtmh.2012.11-0371

Table 2.

Cysticidal efficacy of different antiparasitic regimens for porcine cysticercosis*

Group description Group Viable cysts in muscle Viable cysts in brain
Median (range) P P§ Efficacy, % Median (range) P P§ Efficacy, %
No treatment 7 7,078 (2,072–11,746) Ref. Ref. Reference 25 (16–53) Ref. Ref. Reference
PZQ alone 2 6,515 (2,260–7,985) 0.873 0.09 8.0 46 (6–82) 0.631 0.07 0
Prednisone 6 5,401 (2,121–10,926) 1.00 0.02 23.7 38 (26–54) 0.273 0.02 0
NZX 5 9,433 (7,433–12,731) 0.423 0.01 0 18 (8–54) 0.631 0.12 28
OFZ 4 0 (0–0) 0.003 0.90 100 10 (1–13) 0.055 0.34 60
ABZ + PDN 1 0 (0–0) 0.004 0.90 100 0 (0–4) 0.017 0.39 100
ABZ + PZQ + PDN 3 0 (0–0) 0.005 0.90 100 0 (0–0) 0.009 0.41 100
½ ABZ + PZQ + PDN 8 0 (0–0) 0.002 0.90 100 0 (0–1) 0.007 0.34 100
ABZ + PZQ + 2 PDN 9 0 (0–0) 0.002 0.90 100 0 (0–1) 0.007 0.41 100
*

Ref. = referent; PZQ = praziquantel; NZX = nitazoxanide; OFZ = oxfendazole; ABZ = albendazole; PDN = prednisone.

Numbers of cysts in muscle are adjusted by weight.

Mann-Whitney test (compared with the reference group).

§

Power.