Skip to main content
. Author manuscript; available in PMC: 2013 Nov 1.
Published in final edited form as: Cancer. 2012 Apr 19;118(21):5384–5394. doi: 10.1002/cncr.27538

Table 1.

Distribution of covariates in analyzed case-control population and covariate association with serum autoantibody levels in control participants

Factor NR2E3 MAPK9 CTDSP1
Case N=300 Control N=300 Case Control Case Control Case Control
n (%) n ( %) 50% 75% 50% 75% 50% 75% 50% 75% 50% 75% 50% 75%
Sex
    Men 163 (54) 162 (54) 0.79 0.99 0.75 0.84 0.80 0.90 0.77 0.85 1.09 1.30 1.03 1.26
    Women 137 (46) 138 (46) 0.84 1.10 0.76 0.86 0.81 0.93 0.74 0.85 1.06 1.28 1.01 1.18
                P-value * 0.75 1.0 0.26
Education (years)
    <12 37 (12) 22 (7) 0.79 1.00 0.76 0.88 0.78 0.86 0.83 0.88 1.05 1.18 1.03 1.22
    12 91 (30) 65 (22) 0.80 1.09 0.75 0.85 0.81 0.93 0.74 0.82 1.03 1.26 0.94 1.16
    >12 -<16 76 (26) 82 (27) 0.77 1.04 0.76 0.86 0.77 0.88 0.75 0.88 1.06 1.24 1.02 1.20
    16+ 96 (32) 131 (44) 0.86 1.10 0.75 0.84 0.82 0.91 0.76 0.84 1.15 1.43 1.07 1.28
                P-value * 0.003 0.88 0.16 0.30
Tobacco use
    never 85 (28) 110 (37) 0.78 1.13 0.75 0.83 0.78 0.92 0.74 0.82 1.04 1.19 0.97 1.16
    pipe/cigar 10 (3) 10 (3) 0.85 1.00 0.77 0.80 0.78 0.88 0.79 0.87 1.22 1.38 0.99 1.16
    Former 135 (45) 143 (48) 0.83 1.00 0.77 0.87 0.81 0.91 0.78 0.86 1.10 1.37 1.06 1.30
    current 69 (23) 34 (11) 0.85 1.06 0.74 0.82 0.82 0.93 0.77 0.85 1.09 1.45 0.93 1.26
                P- value * 0.002 0.70 0.67 0.01
Obese
    BMI<30 269 (90) 273 (92) 0.82 1.05 0.75 0.84 0.81 0.92 0.76 0.85 1.08 1.31 1.01 1.21
    BMI 30+ 29 (10) 25 (8) 0.87 1.12 0.80 1.20 0.79 0.93 0.80 1.00 1.06 1.20 1.15 1.47
                P- value * 0.57 0.04 0.10 0.21
Overweight
    BMI<25 154 (52) 177 (59) 0.82 1.02 0.75 0.84 0.81 0.91 0.74 0.84 1.07 1.30 0.98 1.18
    BMI 25+ 144 (48) 121 (41) 0.83 1.10 0.77 0.88 0.80 0.92 0.78 0.87 1.09 1.29 1.08 1.27
                P- value * 0.06 0.14 0.05 0.12
Diabetes
    No diabetes 258 (94) 271 (92) 0.82 1.06 0.75 0.85 0.81 0.92 0.75 0.85 1.07 1.26 1.02 1.21
    Diabetes 5+ yrs 18 (6) 22 (8) 0.86 1.13 0.78 0.84 0.82 0.93 0.82 0.87 1.13 1.40 1.07 1.31
                P- value * 0.65 0.22 0.78 0.29
Allergy history
    No 168 (56) 148 (49) 0.82 1.08 0.76 0.84 0.80 0.93 0.75 0.85 1.08 1.31 1.02 1.20
    Yes 132 (44) 152 (51) 0.83 1.05 0.75 0.86 0.81 0.90 0.77 0.85 1.09 1.27 1.03 1.26
                P- value * 0.10 0.63 0.46 0.40
    Plants/pollen** 105 (35) 113 (38) 0.82 1.04 0.75 0.84 0.80 0.92 0.74 0.85 1.11 1.32 1.02 1.22
    Other allergen** 25 (8) 33 (11) 0.86 1.32 0.78 0.84 0.81 1.00 0.78 0.85 0.95 1.19 1.03 1.16
                P- value * 0.27 0.66 0.32 0.31
No. of allergies
    0 168 (56) 148 (49) 0.83 1.05 0.76 0.86 0.81 0.90 0.77 0.85 1.09 1.27 1.03 1.26
    1 67 (23) 66 (22) 0.84 1.27 0.75 0.84 0.80 1.00 0.74 0.85 1.08 1.36 1.00 1.20
    2 33 (11) 40 (14) 0.75 0.95 0.76 0.83 0.78 0.90 0.74 0.85 1.09 1.21 1.08 1.21
    3 or more 30 (10) 40 (14) 0.86 1.02 0.75 0.86 0.82 0.91 0.74 0.85 1.05 1.32 1.04 1.24
                P- value * 0.34 0.50 0.44 0.61
*

H0: disease status is independent of the covariate; In controls only, H0: autoantibody level (grouped by 75th percentile) is independent of covariate

**

Referent is no allergy history

BMI= Body Mass Index (weight in kg/ height in m2); yrs= years; No.= number