Table 3.

Association between pancreatic cancer and level of serum autoantibody, odds ratios (OR) and 95% confidence intervals (CI) from age and sex-adjusted logistic models

	Cases (N=300)	Controls (N=300)	OR	95% CI	P-value
CTDSP1
Q1	65	89	1.0
Q2	77	70	1.5	(0.96-2.4)
Q3	77	75	1.4	(0.90-2.2)
Q4	81	66	1.7	(1.1 -2.6)
P trend					0.04
MAPK9
Q1	61	91	1.0
Q2	69	77	1.3	(0.84-2.1)
Q3	80	77	1.5	(0.98-2.5)
Q4	90	55	2.4	(1.5 -3.9)
P trend					0.0002
NR2E3
Q1	50	89	1.0
Q2	76	85	1.6	(1.0 -2.5)
Q3	71	79	1.6	(1.0 -2.6)
Q4	103	47	4.0	(2.4 -6.5)
P trend					<0.0001
CTDSP1
<Q4	219	234	1.0
Q4	81	66	1.3	(0.90-1.9)
					0.15
MAPK9
<Q4	210	245	1.0
Q4	90	55	1.9	(1.3 -2.8)
					0.0009
NR2E3
<Q4	197	253	1.0
Q4	103	47	2.9	(1.9 -4.3)
					<0.0001
No. of AAs with levels in Q4
0 (none)	158	198	1.0	(referent)
1 of 3	55	55	1.2	(0.81-1.9)
2 of 3	42	28	1.9	(1.1 - 3.2)
3 of 3	45	19	3.0	(1.7 -5.4)
P trend			1.4	(1.2 -1.7)	<0.0001

* Autoantibody serum level fit as a continuous variable in age and sex-adjusted logistic model

Q4 = 4^th quartile, AAs= autoantibodies