Table 1.
Socio-demographic, behavioural and clinical characteristics of 682 ACCESS participants stratified by at least 95% adherence to ART in first year
| Characteristic | < 95% adherence 450 (66.0%) | ≥95% adherence 232 (34.0%) | Odds Ratio | 95% Confidence Interval | p-value |
|---|---|---|---|---|---|
| ART initiation year | |||||
| Per year increase | 1999 (1997–2004) | 2003 (1998–2007) | 1.13 | 1.09–1.17 | < 0.001 |
| Gender1 | |||||
| Male | 270 (60.0) | 164 (70.7) | 1.00 | ||
| Female | 180 (40.0) | 68 (29.3) | 0.62 | 0.44–0.87 | 0.006 |
| Age1 | |||||
| < 24 years | 21 (4.7) | 3 (1.3) | 1.00 | ||
| ≥ 24 years | 429 (95.3) | 229 (98.7) | 3.74 | 1.10–12.66 | 0.034 |
| Aboriginal ancestry1 | |||||
| No | 278 (61.8) | 161 (69.4) | 1.00 | ||
| Yes | 172 (38.2) | 71 (30.6) | 0.71 | 0.51–0.99 | 0.050 |
| Heroin use2 | |||||
| < Daily | 347 (77.1) | 195 (84.1) | 1.00 | ||
| ≥ Daily | 103 (22.9) | 37 (15.9) | 0.64 | 0.42–0.97 | 0.034 |
| Cocaine use2 | |||||
| < Daily | 320 (71.1) | 202 (87.1) | 1.00 | ||
| ≥ Daily | 130 (28.9) | 30 (12.9) | 0.37 | 0.24–0.56 | < 0.001 |
| Crack cocaine use2 | |||||
| < Daily | 321 (71.3) | 172 (74.1) | 1.00 | ||
| ≥ Daily | 129 (28.7) | 60 (25.9) | 0.88 | 0.61–1.26 | 0.475 |
| Methadone use3 | |||||
| No | 276 (61.3) | 150 (64.7) | 1.00 | ||
| Yes | 174 (38.7) | 82 (35.3) | 0.87 | 0.62–1.21 | 0.396 |
| Unstable housing3 | |||||
| No | 155 (34.4) | 78 (33.6) | 1.00 | ||
| Yes | 295 (65.6) | 154 (66.4) | 1.04 | 0.74–1.45 | 0.830 |
| Plasma HIV RNA load | |||||
| Per log10 increase | 4.9 (4.4–5.1) | 4.9 (4.4–5.0) | 0.91 | 0.72–1.15 | 0.426 |
| CD4+ cell count | |||||
| Per 100 cells | 2.4 (1.4–3.7) | 1.9 (1.2–3.0) | 0.89 | 0.81–0.97 | 0.008 |
1
Time-varying, refers to the six month period prior to baseline
2
Time-varying, refers to current status