Effects of intrathecal administration of ALX-1393 on (a) intercontraction interval and (b) pressure threshold in the presence or absence of strychnine in cyclophosphamide rats. Each bar represents the mean plus or minus the standard error of the mean.
ICI = intercontraction interval; PT = pressure threshold; - = vehicle (dimethyl sulfoxide or saline); ANOVA = analysis of variance.
* p < 0.05.
** p < 0.01 (compared among three groups; one-way ANOVA followed by Bonferroni multiple comparison test); the number of animals (n) in each subgroup was shown in parentheses.