Skip to main content
. Author manuscript; available in PMC: 2012 Aug 9.
Published in final edited form as: Curr Pharm Des. 2012;18(17):2404–2415. doi: 10.2174/13816128112092404

Fig. (1). Desmoplasia.

Fig. (1)

The desmoplasia consisting of fibroblasts, pancreatic stellate cells, lymphatic and vascular endothelial cells, immune cells, pathologic increased nerves, and ECM creates a complex tumor microenvironment that promotes pancreatic cancer development, invasion, metastasis and resistance to chemotherapy. Targeting the interaction between cancer and stroma in the pancreatic tumor microenvironment may contribute to the design of new diagnosis techniques and treatments for this disease.