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. Author manuscript; available in PMC: 2012 Aug 9.
Published in final edited form as: Curr Pharm Des. 2012;18(17):2404–2415. doi: 10.2174/13816128112092404

Fig. (3). Paracrine regulation of pancreatic cancer cell invasion by peripheral nerves via NGF, GDNF, and neurotransmitter.

Fig. (3)

Peripheral nerves in a tumor’s microenvironment may influence the biological behavior of cancer cells, which can contribute to tumor progression. Paracrine regulation of the pancreatic cancer invasion by nerves may have important implications for potential therapy directed against nerve invasion by cancer.