Table 1.
Mean value of observables characterizing tissue geometry, topology, and stress distribution for the different cell division modes at high and low intrinsic noise level.
| Low intrinsic noise | Division mode | ||||
|---|---|---|---|---|---|
| Observable | Moment of area | Stress | Previous plane | Random | Equal area |
| Stress variability | 0.99 ± 0.06 | 1.02 ± 0.06 | 1.06 ± 0.04 | 1.24 ± 0.1 | 1.24 ± 0.1 |
| Stress anisotropy | 0.64 ± 0.03 | 0.63 ± 0.03 | 0.65 ± 0.02 | 0.62 ± 0.03 | 0.63 ± 0.05 |
| Area | 0.915 ± 0.009 | 0.920 ± 0.008 | 0.929 ± 0.005 | 0.953 ± 0.01 | 0.950 ± 0.02 |
| Number of edges | 5.77 ± 0.09 | 5.77 ± 0.09 | 5.76 ± 0.05 | 5.74 ± 0.1 | 5.74 ± 0.2 |
| Shape | 0.0669 ± 0.0004 | 0.0665 ± 0.0004 | 0.0649 ± 0.0003 | 0.0612 ± 0.0007 | 0.0613 ± 0.0009 |
| Squared angle | 4.5 ± 0.2 | 4.5 ± 0.1 | 4.5 ± 0.1 | 4.5 ± 0.2 | 4.5 ± 0.3 |
| High intrinsic noise | Division mode | ||||
| Stress variability | 0.96 ± 0.03 | 1.03 ± 0.04 | 1.06 ± 0.04 | 1.25 ± 0.1 | 1.25 ± 0.1 |
| Stress anisotropy | 0.64 ± 0.02 | 0.63 ± 0.02 | 0.65 ± 0.02 | 0.62 ± 0.04 | 0.62 ± 0.03 |
| Area | 0.921 ± 0.006 | 0.917 ± 0.01 | 0.930 ± 0.005 | 0.946 ± 0.01 | 0.945 ± 0.01 |
| Number of edges | 5.77 ± 0.06 | 5.77 ± 0.06 | 5.76 ± 0.05 | 5.74 ± 0.2 | 5.74 ± 0.1 |
| Shape | 0.0670 ± 0.0002 | 0.0665 ± 0.0002 | 0.0649 ± 0.0003 | 0.0611 ± 0.0009 | 0.0612 ± 0.0007 |
| Squared angle | 4.5 ± 0.1 | 4.5 ± 0.1 | 4.5 ± 0.1 | 4.5 ± 0.2 | 4.5 ± 0.2 |
Average is taken over all feedback strengths considered. Notably stress variability is about 20% lower for cell divisions along the maximum principal second moment of area or stress or for cell divisions perpendicular to the previous cell division plane than in any other case. Also the area of cells in these two cases is smaller and the shape more circular. There are no significant changes between the cases of high and low intrinsic noise level.