Table 2.
Univariate Cox Regression Analyses for OS, BCSS and RFS
| Variables |
OS |
BCSS |
RFS |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| Age |
1.07 |
1.04-1.09 |
.000 |
1.05 |
1.02-1.09 |
.003 |
1.04 |
1.01-1.07 |
.012 |
| Lymph node status |
|
|
|
|
|
|
|
|
|
| - vs. + |
2.59 |
1.30-5.14 |
.007 |
5.57 |
1.85-16.78 |
.002 |
6.70 |
2.52-17.80 |
.000 |
| Tumor size |
|
|
|
|
|
|
|
|
|
| >20 vs. ≤20 mm |
2.53 |
1.31-4.89 |
.006 |
3.04 |
1.19-7.78 |
.02 |
3.14 |
1.34-7.10 |
.006 |
| Ki67 |
3.00 |
1.51-5.96 |
.002 |
3.99 |
1.38-11.50 |
.01 |
1.68 |
0.82-3.44 |
.16 |
| Grade |
2.11 |
1.28-3.49 |
.004 |
5.14 |
2.03-13.00 |
.001 |
3.18 |
1.62-6.25 |
.001 |
| HER |
3.75 |
1-57-8.99 |
.003 |
7.69 |
2.98-19.86 |
.000 |
7.13 |
3.01-16.90 |
.000 |
| ER |
0.39 |
0.19-0.79 |
.009 |
0.23 |
0.10-0.55 |
.001 |
0.28 |
0.13-0.60 |
.001 |
| CD163 in TS |
2.66 |
1.28-5.55 |
.009 |
3.20 |
1.20-8.54 |
.02 |
2.12 |
0.83-5.39 |
.12 |
| CD68 in TS |
0.16 |
0.07-0.35 |
.000 |
15.2 |
5.45-42.45 |
.000 |
9.24 |
3.64-23.48 |
.000 |
| CD163 in TN |
0.32 |
0.04-2.37 |
.27 |
1.45 |
0.33-6.32 |
.62 |
1.06 |
0.25-4.55 |
.94 |
| CD68 in TN | 0.05 | 0.00-21.70 | .33 | 0.44 | 0.00-169.12 | .46 | 0.04 | 0.00-43.30 | .37 |
Abbreviations: OS, overall survival; BCSS, breast cancer specific survival; RFS, recurrence free survival; HR, hazard ratio.