Table 3.
Multivariate Cox Regression Analyses for OS, BCSS and RFS
| Variables |
OS |
BCSS |
RFS |
||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P | HR | 95% CI | P | HR | 95% CI | P | |
| Age |
1.07 |
1.03-1.10 |
.000 |
1.05 |
1.00-1.09 |
.03 |
1.03 |
1.00-1.07 |
.07 |
| Lymph node status |
|
|
|
|
|
|
|
|
|
| - vs. + |
1.81 |
0.87-3.82 |
.12 |
3.28 |
1.01-10.63 |
.05 |
4.94 |
1.77-13.80 |
.002 |
| Tumor size |
|
|
|
|
|
|
|
|
|
| >20 vs. ≤20 mm |
1.58 |
0.65-3.81 |
.31 |
2.47 |
0.60-10.08 |
.21 |
2.12 |
0.72-6.24 |
.17 |
| Ki67 |
3.06 |
1.05-8.93 |
.04 |
4.40 |
0.67-28.82 |
.12 |
0.45 |
0.13-1.53 |
.20 |
| Grade |
0.63 |
0.27-1.49 |
.29 |
0.86 |
0.20-3.67 |
.84 |
2.25 |
0.78-6.56 |
.14 |
| HER |
3.45 |
1.16-10.24 |
.03 |
5.37 |
1.61-17.90 |
.006 |
4.46 |
1.63-12.20 |
.004 |
| ER |
0.47 |
0.17-1.35 |
.16 |
0.39 |
0.11-1.41 |
.15 |
0.37 |
0.12-1.13 |
.08 |
| CD163 in TS |
0.62 |
0.24-1.58 |
.32 |
0.74 |
0.23-2.38 |
.61 |
0.91 |
0.30-2.72 |
.86 |
| CD68 in TS | 2.96 | 0.87-10.11 | .08 | 0.12 | 0.02-0.72 | .02 | 0.29 | 0.08-1.10 | .07 |
Abbreviations: OS, overall survival; BCSS, breast cancer specific survival; RFS, recurrence free survival; HR, hazard ratio.