Table 1.
Immunostainings of Fos, CGRP, and microglia in the central nervous system of affected and unaffected mice
| Fos | CGRP |
Microglia |
|||
|---|---|---|---|---|---|
| Cerebral cortex | Hippocampus | Spinal cord | |||
| Unaffected |
71.65 ± 13.84 (n = 5) |
792.33 ± 60.20 (n = 5) |
146.10 ± 8.42 (n = 6) |
242.83 ± 17.75 (n = 6) |
213.15 ± 13.13 (n = 6) |
| Affected (5 weeks) |
102.19 ± 13.53 (n = 8) |
1512.23 ± 231.54* (n = 6) |
413.85 ± 5.61* (n = 3) |
593.12 ± 18.92* (n = 3) |
1023.89 ± 15.04 ** (n = 3) |
| Affected (20 weeks) | 500.79 ± 244.11 (n = 5) | 361.14 ± 57.71# (n = 5) | 247.78 ± 24.71# (n = 5) | ||
Values are expressed as the density of immunostaining in a standard unit area of 200 μm × 200 μm (mean ± SEM). *p < 0.05, **p < 0.01, significant difference between the unaffected and affected (5 weeks) groups. #p < 0.05, significant difference between the affected (5 weeks) and affected (20 weeks) groups.