Figure 2.

Self-assembled chromatin plates having partially unfolded layers. In some experiments metaphase chromatin fragments extensively dialyzed at 4°C against the self-assembly solution produced plates having regions with a granular texture in the upper layers (indicated by asterisks); the dimensions of the granules suggest that they correspond to unorganized nucleosomes in chromatin filaments not yet incorporated into well-defined layers. Scale bar: 200 nm.