Figure 4.

Self-assembly of chromatin plates in experiments performed at different temperatures. Metaphase chromatin fragments were spread on carbon-coated grids by centrifugation, then the grids immersed in a solution of chromatin fragments were dialyzed for different times against the self-assembly solution at different temperatures. TEM images corresponding to samples incubated at 25°C for 24 h (A) and at 37°C for 7 h (B). Scale bars: 200 nm.