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Changes in surface pressure of lipid monolayers, upon insertion of Aβ42 monomers at varying initial pressures. (A) A representative experiment, obtained with SM/Chol/DMPA (40/40/20) at 15 mN/m. (B) Equilibrium values. ●, SM/Chol (1:1), ▴, SM/Chol/DMPA (47.5/47.5/5), ■, SM/Chol/DMPA (40/40/20). Average values mean ± SE (n = 3). Aβ42 stock solution was 50 μM. Aβ42 final concentration in the trough was 1.22 μM.
