Table 1.
Biophysical properties of normal peripheral blood cells and breast cancer associated HD-CTCs.
| Cell type | Area [μm2] | Volume [fL] | LC [μm] | σA[−] | N |
|---|---|---|---|---|---|
| PLT | 7.5 ± 0.3 | 10.5 ± 0.5 | 0.42 ± 0.03 | 0.06 ± 0.01 | 30 |
| RBC | 42.0 ± 1.0 | 100.6 ± 4.0 | 1.19 ± 0.05 | 0.06 ± 0.01 | 20 |
| Leukocyte | 48.0 ± 0.6 | 234.1 ± 4.1 | 0.87 ± 0.03 | 0.17 ± 0.05 | 100 |
| HD-CTC | 135.6 ± 6.0* | 851.6 ± 45.8* | 0.80 ± 0.04* | 0.12 ± 0.04* | 42 |
*
Denotes p < 0.001 with respect to leukocytes. Leukocytes and HD-CTCs are from the same patient while PLTs and RBCs were collected from healthy donors.