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Histological sections of intestinal segments treated according to (A) control, (B) positive control conditions, and (C) blank SDEDDS (H&E stain, × 100). (D) Effect of blank SDEDDS on the cytotoxicity of Caco-2 cells after incubation for 2 hours.
Note: Formulation was removed, and culture was continued up to 48 hours.
Abbreviations: H&E, hematoxylin and eosin; HSYA, Hydroxysafflor yellow A; SDEDDS, self-double-emulsifying drug delivery system.
