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. Author manuscript; available in PMC: 2012 Nov 7.
Published in final edited form as: Phys Chem Chem Phys. 2011 Mar 14;13(41):18288–18296. doi: 10.1039/c1cp20277d

Table 2.

Average and maximum charge states for different forms of ribonuclease A (RNase A) as a function of m-NBA concentration in the electrospray solution.

Average (Maximum) Charge (+)
% m-NBA
RNase A 0 0.5 1.0 1.5
Native 6.9 (8) 8.9 (12) 9.8 (12) 10.2 (13)
Carboxymethylated
(19+ – 10+)		 14.1 (19) 13.2 (19) 13.1 (19) 12.5 (19)
Carboxymethylated
(9+ – 7+)		 7.8 (N/A) 8.4 (N/A) 8.6 (N/A) 8.7 (N/A)
Native 6.9 (8) 8.4 (11) 9.8 (12) 10.3 (13)
Carbamidomethylated
(19+ – 10+)		 13.7 (19) 13.2 (18) 12.8 (19) 13.1 (19)
Carbamidomethylated
(9+ – 7+)		 7.8 (N/A) 8.7 (N/A) 8.7 (N/A) 8.6 (N/A)