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. Author manuscript; available in PMC: 2012 Aug 9.
Published in final edited form as: Nat Immunol. 2005 Apr 10;6(5):490–496. doi: 10.1038/ni1187

Figure 6.

Figure 6

MHC contacts made by the Ob.1A12 and HA1.7 TCRs. (a,b) Differences in the contribution of germline-encoded CDR1 and CDR2 loops from the Ob.1A12 (a) and HA1.7 (b) TCRs to MHC binding. CDR1 loops, α1 and β1; CDR2 loops, α2 and β2. (c,d) Differences in positions of CDR3 loops on the MHC helices for the Ob.1A12 (c) and HA1.7 (d) TCRs. CDR3α and CDR3β loops, α3 and β3, respectively. Ob.1A12 TCRβ residues encoded by N-region residues and corresponding MHC contacts are circled. Red, TCRβ loops; yellow, TCRα loops.