Table 2. Open Field Activities and Relative Sucrose Intake (%) of All Groups at Baseline and at 28 Days after Ischemia.
| Group(n) | Locomotor | Activity | Rearing | Activity | Sucrose | preference (%) |
| Baseline | Day28 ISCH | Baseline | Day28 ISCH | Baseline | Day28 ISCH | |
| CON(6) | 51.9±2.1 | 45.9±2.3 | 18.4±1.3 | 16.5±0.8 | 72.7±2.5 | 71.3±2.0 |
| CMS(6) | 52.1±1.8 | 40.1±2.0a | 17.8±0.8 | 11.2±0.7a | 71.7±2.6 | 62.1±3.1a |
| ISCH (6) | 50.9±1.7 | 42.1±2.1b | 18.1±1.0 | 12.1±0.6a | 71.8±2.0 | 68.9±2.0 |
| MCAO+CMS(6) | 51.1±2.0 | 35.6±1.6a | 18.0±1.4 | 9.4±0.7a | 71.5±3.1 | 52.6±1.8a |
| MCAO+CMS+D(6) | 51.9±2.0 | 36.5±1.4 | 18.4±1.8 | 11.8±1.5c | 71.8±2.7 | 63.4±2.1c |
Locomotor activity was defined as at least three paws in a quadrant and rearing behaviour defined as the animal standing upright on its hind legs.
The sucrose preference was calculated according to the following ratio: SP = sucrose intake (g)/sucrose intake (g) + water intake (g).
Values are means±S.D. See text for the results of relevant statistical tests. CON, control; CMS, chronic mild stress; ISCH, ischemic stroke; MCAO, middle cerebral artery occlusion; D, DAPT(N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phenyl-glycine t-butyl ester).
a
P<0.001CMS, ISCH and MCAO+CMS vs. their respective CON value.
b
P<0.05 ISCH vs. their respective CON value.
c
P<0.01 MCAO+CMS +DAPT vs. MCAO+CMS value.