Figure 7. Binding dynamics of monomeric and heptameric targeting ligands by BIAcore analysis.

The extracellular domain of (A) EGFR and (B) HER2 receptors were immobilized on the CM5 chip. Different concentrations of monomer or heptamer proteins were injected into the channels. Analyses were performed at room temperature at a flow rate of 20 µl/min.