Figure 11. Analysis of cellular toxicity of heptameric targeting ligands by the MTS assay.

A431 and SK-OV3 cells were incubated with various concentrations from 250 nM to 4 µM of each heptameric targeting ligand for 24 h at 37°C. Cisplatin (4 µM) was used as a positive control. Cells without the targeting ligands or without cisplatin were used as a negative control. Absorbance at 490 nm (A490) was measured.