Figure 1. Sequence comparison of murine MK5 splice variants.
Figure showns the predicted amino acid sequences. Roman numerals above sequence refer to subdomains (I–IX) conserved in all protein kinases. The catalytic domain (residues 22-304) is indicated by a solid line above the sequence. The consensus nuclear export sequence (NES) is underlined with a solid line and the nuclear localization sequence (NES) is in bold letters. Thr-182, the site of phosphorylation by p38 MAPK is indicated by an asterisk. The ERK3/4 binding site is indicated. Dashes represent gaps.
