Table 1.
Summary of Outcomes for Variants by Original Inclusion Criteria
| Reason for Original Inclusion (n = 5,788) | Failed or Excluded |
Present in Controls, p < 0.05 |
Absent in Controls |
||||||
|---|---|---|---|---|---|---|---|---|---|
| In African Americans Only | In European Ancestry Only | In Both Ancestral Groups | In Neither Ancestral Group | In 0 Additional Cases | In 1 Additional Case | In > 1 Additional Case | |||
| p < 0.05 (n = 428) | allelic (n = 242) | 30 | 3 | 28 | 2 | 173 | 4 | 2 | 0 |
| recessive (n = 186)a | 37 | 5 | 11 | 1 | 131 | 1 | 0 | 0 | |
| In > 1 case and 0 controls (n = 861) | allelic (n = 843) | 94 | 9 | 15 | 0 | 476 | 192 | 34 | 23 |
| recessive (n = 18)a | 2 | 0 | 1 | 0 | 12 | 2 | 1 | 0 | |
| In 1 case and 0 controls (n = 4,498) | allelic (n = 4,280) | 434 | 28 | 9 | 0 | 1,443 | 1,929 | 301 | 136 |
| recessive (n = 218)a | 36 | 2 | 3 | 0 | 103 | 60 | 7 | 7 | |
a
p values are given for recessive tests; counts are for homozygous genotypes.