Table 3.
Association of Prostate Cancer with HOXB13 G84E (rs138213197) on chromosome 17q21.32.
| Affected in Pedigreea | Carrier Rate (%) | OR (95% CI) | P |
|---|---|---|---|
| 0 | 2 of 825 (0.002) | ||
| 1 | 4 of 268 (0.015) | 5.6 (0.9 – 33.9) | 0.061 |
| ≥ 1 | 20 of 1126 (0.018) | 7.2 (1.7 – 31.2) | 8.1 × 10−3 |
| 2 | 7 of 529 (0.013) | 5.8 (1.2 – 28.2) | 0.030 |
| ≥ 2 | 16 of 858 (0.019) | 7.9 (1.8 – 34.5) | 6.2 × 10−3 |
| ≥ 3 | 9 of 329 (0.027) | 11.8 (2.5 – 55.3) | 1.8 × 10−3 |
| ≥ 4 | 2 of 125 (0.016) | 7.0 (1.0 – 51.4) | 0.055 |
a
First and second degree relatives (0, controls; 1, case probands with no others in pedigree affected; 2, case probands with one additional in pedigree affected, etc).