Fig. 2.
Median number of neoplastic cell foci in the lungs of mice determined 21 days after iv injection of KHT sarcoma cells. In (a) 5×103 (squares, triangles) and 2×103 (circles) KHT cells were injected. In (b) 2×103 KHT cells were used. Treatment in (a) was daily 10 mg/kg doses of saracatinib commencing on day 1; treatment in (b) was 10 mg/kg administered daily on days 3–7 and 10–14. Bars and hatched areas = 90% and 75% confidence intervals, respectively; stars = statistical significance of p < 0.05 (Wilcoxon’s rank-sum test) compared with controls.
