Table 1.
Characteristics of the Study Subjects at the Different Baseline Ages
| 50 years | 60 years | 71 years | 82 years | |
|---|---|---|---|---|
| n | 2322 | 1852 | 1221 | 526 |
| Age, year, mean (SD) | 49.6 (0.6) | 59.8 (1.8) | 71.0 (0.6) | 81.7 (0.9) |
| FRAX variables | ||||
| Height, cm, mean (SD) | 176 (6) | 176 (6) | 175 (6) | 173 (6) |
| Weight, kg, mean (SD) | 77.8 (11.1) | 78.7 (11.4) | 80.3 (11.5) | 78.1 (11.2) |
| BMI, kg/m2, mean (SD) | 25.0 (3.2) | 25.5 (3.3) | 26.3 (3.4) | 26.1 (3.4) |
| Previous fracture | 26 (1) | 110 (6) | 138 (11) | 104 (20) |
| Parent fractured hipa | 109 (5) | 106 (6) | 109 (9) | 47 (9) |
| Current smoker | 1185 (51) | 584 (32) | 173 (14) | 31 (6) |
| Glucocorticoids | 7 (0.3) | 17 (0.9) | 119 (10) | 40 (8) |
| Rheumatoid arthritis | 0 (0) | 0 (0) | 3 (0.2) | 4 (0.8) |
| Secondary osteoporosisb | 19 (0.8) | 21 (1) | 19 (2) | 11 (2) |
| High alcohol consumption | 222 (10) | 222 (12) | 134 (11) | 52 (10) |
| Medications | ||||
| None | 2100 (90) | 1163 (63) | 404 (33) | 87 (16) |
| Comorbidities | ||||
| None | 2149 (92) | 1192 (64) | 478 (39) | 108 (20) |
| 1 comorbidity | 142 (6) | 411 (22) | 355 (29) | 109 (21) |
| 2 comorbidities | 23 (1) | 146 (8) | 199 (16) | 92 (17) |
| ≥3 comorbidities | 8 (0.3) | 103 (5) | 189 (15) | 217 (41) |
| Cardiovascular disease | 35 (2) | 217 (12) | 316 (26) | 263 (50) |
| Cancer | 6 (0.3) | 33 (2) | 75 (6) | 85 (16) |
| Other diseases | 140 (6) | 532 (29) | 589 (48) | 352 (67) |
| Behavioral factors | ||||
| Former smoker | 552 (24) | 721 (39) | 574 (47) | 52 (10) |
| Low leisure-time physical activity level | 337 (14) | 221 (12) | 61 (5) | 79 (15) |
| Moderate leisure-time physical activity level | 884 (38) | 941 (51) | 437 (36) | 189 (36) |
| High leisure-time physical activity level | 1101 (47) | 690 (37) | 723 (59) | 258 (49) |
| Sedentary work | 266 (11) | 234 (13) | Not assessed | Not assessed |
| Physically demanding work | 253 (11) | 160 (9) | Not assessed | Not assessed |
| Married | 1999 (86) | 1541 (83) | 985 (81) | 381 (72) |
| Living alone | Not assessed | Not assessed | 192 (16) | 137 (26) |
| Educational level less than high school | 1931 (83) | 1556 (84) | 1002 (82) | 406 (77) |
| Impaired cognitive function | Not assessed | Not assessed | 140 (12) | 173 (33) |
Data are given as number (percentage) of men unless otherwise stated.
a
Assessed at age 71 years.
b
Secondary osteoporosis includes: liver disease, type 1 diabetes mellitus, malnutrition, thyreotoxicosis, hypogonadism.