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. 2012 May;166(1):177–193. doi: 10.1111/j.1476-5381.2011.01659.x

Figure 5.

Figure 5

Differential effects of modulating the IL-13 axis on the allergic phenotype in WT BALB/c (A–D) and huIL-13 knock-in BALB/c (E-H) mice. (A and E) BAL eosinophilia with inset % eosinophils (n= 14–16); (B and F) FEV (n= 8); (C and G) AHR (n= 4–8); (D) BAL muIL-13 and (H) BAL huIL-13 (n= 15–16). Data are shown as mean average ± SEM from two blocked experiments. *P < 0.05; **P < 0.01; ***P < 0.001, significantly different from values in the sensitization and challenge (s/c) group; one-way (two-way for AHR) anova followed by Dunnett's (Bonferroni's for AHR) multiple comparisons test.