Figure 6.
Effect of i.c.v. Gαs ODN pre-treatment on the cardiovascular and renal excretory responses to central guanabenz administration in conscious male Sprague-Dawley rats. The values are means ± SEM and illustrate the cardiovascular and renal effects of i.c.v. guanabenz (50 µg) in six conscious rats per group that were pre-treated (24 h) with i.c.v. SCR ODN (25 µg in 5 µL) or a Gαs ODN (25 µg in 5 µL). Data for SCR ODN pre-treatment (pt) are transposed from Figure 1 for comparison and clarity. Abbreviations as in Figure 1. *P < 0.05, compared with respective group control value (designated C);one-way repeated measures anova. τP < 0.05, compared with SCR ODN pt group value at respective time point; two-way repeated measures anova.