Table 1.

Genes significantly Up/Down-regulated greater than 2 fold in UOK268 in comparison to the HK-2 cell line.

Symbol	Significantly Up-Regulated Genes in UOK268 vs HK-2
	FC (Raw)	FC (Log2)	p-value	FDR (%)
RHOT2	12.00	3.58	0.000	0.65
CPT1C	7.86	2.98	0.000	0.70
MT1G	5.48	2.45	0.003	1.93
THAP3	4.11	2.04	0.000	0.62
SLC25A44	3.75	1.91	0.011	3.58
MDH1	3.66	1.87	0.018	4.72
MT1E	3.60	1.85	0.011	3.52
TRND	3.58	1.84	0.000	0.56
SLC25A14	3.49	1.80	0.004	2.09
HSPA13	3.45	1.79	0.001	1.00
MIPEP	3.40	1.77	0.002	1.25
NKRF	3.35	1.75	0.000	0.34
CKB	3.33	1.73	0.012	3.69
UBB	3.28	1.72	0.014	4.08
DHPS	3.27	1.71	0.048	8.52
FH	3.15	1.65	0.024	5.65
P4HB	3.14	1.65	0.019	4.78
UBE2K	3.00	1.59	0.002	1.61
ALAS2	2.91	1.54	0.044	8.06
YWHAE	2.88	1.52	0.006	2.63
GPX7	2.87	1.52	0.022	5.30
SLC25A29	2.85	1.51	0.017	4.59
ACBD3	2.83	1.50	0.014	4.09
RNR1	2.82	1.50	0.001	1.00
LRRC16B	2.78	1.47	0.035	6.89
SLC40A1	2.76	1.46	0.004	2.20
PLA2G1B	2.69	1.43	0.043	7.93
CASP5	2.64	1.40	0.000	0.70
ACAA1	2.58	1.37	0.000	0.58
MTHFD1	2.53	1.34	0.006	2.54
RHOT1	2.47	1.30	0.007	2.80
ETFA	2.43	1.28	0.002	1.47
HADHA	2.39	1.26	0.002	1.47
ATPAF2	2.37	1.24	0.021	5.13
RPL5	2.30	1.20	0.024	5.65
ETFDH	2.28	1.19	0.023	5.47
SYNPR	2.26	1.18	0.007	2.90
LOC100293864	2.21	1.14	0.017	4.59
ALDH18A1	2.19	1.13	0.000	0.52
HCCS	2.18	1.12	0.010	3.39
APP	2.12	1.09	0.000	0.50
MRPS11	2.12	1.08	0.009	3.17
GRB10	2.11	1.08	0.001	0.88
MTND5	2.11	1.08	0.053	9.00
NR4A1	2.09	1.07	0.001	0.88
PCK2	2.09	1.07	0.006	2.65
BCO2	2.09	1.06	0.042	7.87
SLC25A37	2.06	1.04	0.030	6.34
MT1B	2.04	1.03	0.005	2.37
COPA	2.01	1.01	0.004	2.14

Symbol	Significantly Down-Regulated Genes in UOK268 vs HK-2
	FC (Raw 1/x)	FC (log2)	p-value	FDR (%)
TIMM8A	32.02	−5.00	0.000	0.29
SLC25A25	8.68	−3.12	0.001	1.00
ATP5F1	6.02	−2.59	0.000	0.50
FXYD1	5.52	−2.46	0.000	0.06
DUOX2	4.90	−2.29	0.000	0.56
CYP2E1	4.67	−2.22	0.000	0.52
RAB5B	4.55	−2.19	0.000	0.50
ACAD9	4.10	−2.04	0.000	0.65
MRPS25	4.07	−2.03	0.005	2.44
PFN1	3.99	−2.00	0.026	5.88
GOT2	3.94	−1.98	0.000	0.65
NDUFV1	3.85	−1.94	0.018	4.60
MTFMT	3.59	−1.84	0.000	0.57
MRPL21	3.53	−1.82	0.000	0.70
ACSBG1	3.47	−1.79	0.004	2.11
TRNL2 (MTTL2)	3.39	−1.76	0.005	2.36
ROPN1B	3.38	−1.76	0.001	0.88
CASP2	3.37	−1.75	0.009	3.17
IMPDH1	3.32	−1.73	0.003	1.91
GSTK1	3.31	−1.73	0.001	0.88
LOC100129794	3.25	−1.70	0.001	0.88
ACP6	3.12	−1.64	0.001	0.75
CACNA2D2	3.11	−1.64	0.004	2.14
LDHA	3.02	−1.59	0.048	8.52
TFB1M	3.01	−1.59	0.002	1.61
CHD3	2.95	−1.56	0.001	1.11
RPS6KC1	2.87	−1.52	0.022	5.30
CYP2C18	2.86	−1.51	0.002	1.36
RAP1B	2.84	−1.50	0.002	1.25
DGUOK	2.83	−1.50	0.043	8.02
TRNL1 (MTTL1)	2.73	−1.45	0.004	2.11
ELOVL1	2.65	−1.40	0.032	6.64
UVRAG	2.60	−1.38	0.025	5.78
MYH4	2.59	−1.38	0.011	3.58
GOT1	2.57	−1.36	0.015	4.20
BCCIP	2.46	−1.30	0.025	5.82
MRPS26	2.44	−1.28	0.049	8.55
ACSL4	2.41	−1.27	0.004	1.99
COX7A2	2.35	−1.23	0.028	6.13
NAT1	2.35	−1.23	0.000	0.52
DIABLO	2.30	−1.20	0.000	0.29
TOMM20	2.29	−1.19	0.028	6.16
HNRPC	2.25	−1.17	0.001	0.88
OGDH	2.25	−1.17	0.003	1.73
SOD1	2.24	−1.16	0.040	7.63
COX7C	2.23	−1.16	0.010	3.25
ALDH6A1	2.21	−1.15	0.000	0.58
DDX27	2.17	−1.12	0.036	7.09
MPHOSPH6	2.11	−1.07	0.048	8.52
ATP5G3	2.10	−1.07	0.053	9.00
FTMT	2.06	−1.04	0.003	1.94
SLC25A46	2.05	−1.04	0.000	0.59
NOX5	2.04	−1.03	0.047	8.52
LONP1	2.01	−1.01	0.009	3.17
NDUFA9	2.01	−1.01	0.016	4.42