Table 2.
Ingenuity® Pathways Analysis software result tables for the most significant molecular/biological functions and canonical pathways.
| Top Molecular and Biological Functions | ||
|---|---|---|
| Cluster Description | Cluster p-value ranges | Total number of selected genes |
|
| ||
| Lipid Metabolism | 1.87E-11 to 1.78E-02 | 57 |
| Small Molecule Biochemistry | 1.87E-11 to 1.78E-02 | 97 |
| Amino Acid Metabolism | 7.39E-08 to 1.78E-02 | 19 |
| Cellular Function and Maintenance | 7.51E-11 to 1.65E-02 | 33 |
| Cellular Compromise | 8.73E-11 to 1.29E-02 | 29 |
| Top Canonical Pathways | ||
|---|---|---|
| Canonical Pathway | p-value | Ratio of selected genes to pathway genes |
|
| ||
| Mitochondrial Dysfunction | 1.60E-24 | 30/169 (0.178) |
| Oxidative Phosphorylation | 8.17E-17 | 25/165 (0.152) |
| Valine, Leucine and Isoleucine Degradation | 1.54E-13 | 16/111 (0.144) |
| Propanoate Metabolism | 1.93E-11 | 14/130 (0.108) |
| Citrate Cycle | 1.16E-10 | 10/58 (0.172) |