Table 3.
Comparisons Between HIV-Uninfected and Virally Suppressed HIV-Infected Adults 96 Weeks After Antiretroviral Treatment
| Unadjusted (95% CI) | Multivariable (95% CI) | |
|---|---|---|
| Parameter | P Value | P Value |
| Including all subjects (n = 443) | ||
| %CD28−CD4+ | −7.1 (−10, −4.2) | −5.4 (−8.5, −2.2) |
| <.01 | <.01 | |
| %CD28−CD8+ | −9.6 (−14, −5.2) | −7.7 (−12, −3.1) |
| <.01 | <.01 | |
| Restricted to those with posttreatment CD4+ >500 cells/μL (n = 234) | ||
| %CD28−CD4+ | −5.0 (−7.6, −2.3) | −3.9 (−7.0, −0.9) |
| <.01 | .01 | |
| %CD28−CD8+ | −8.8 (−13, −4.3) | −7.0 (−12, −2.1) |
| <.01 | .01 | |
| Restricted to those with posttreatment CD4+ >500 cells/μL and pretreatment CD4+ ≥350 cells/μL (n = 146) | ||
| %CD28−CD4+ | −5.6 (−8.6, −2.6) | −5.1 (−8.6, −1.6) |
| <.01 | .01 | |
| %CD28−CD8+ | −9.1 (−14, −4.2) | −7.5 (−13, −1.9) |
| <.01 | .01 | |
Models adjusted for age, race/ethnicity, and sex.
In all models reference group = chronically HIV infected.
Abbreviations: CI, confidence interval; HIV, human immunodeficiency virus.