Figure 1.

K1 subtype analysis of Kaposi sarcoma–associated herpesvirus (KSHV)–multicentric Castleman disease (MCD) and KSHV-associated inflammatory cytokine syndrome (KICS) patients. All K1 sequences collected were translated prior to analysis and were analyzed by bootstrap neighbor-joining analysis with relevant sequences from GenBank. In total, 100 bootstrap replicates were conducted to determine the topology of the trees using MEGA (version 4.0.2). KSHV-MCD patients are indicated by a square and KICS patients are indicated by a triangle. AIDS–Kaposi sarcoma cases and controls are unmarked.