FIGURE 1 .

Analytic framework for (n-3) fatty acid exposure and cardiovascular disease. This framework concerns the effect of (n-3) fatty acid exposure (as a supplement or from food sources) on cardiovascular disease. Populations of interest are noted in the top rectangle, exposure in the oval, outcomes in the rounded rectangles, and effect modifiers in the hexagon. Connecting lines indicate associations and effects. CVD, cardiovascular disease; WBC, white blood cell (leukocyte); RBC, red blood cells (erythrocytes). Adapted from (21).