. 2012 Jun 1;205(Suppl 3):S391–S398. doi: 10.1093/infdis/jis199

Table 2.

Recommended Daily Intake of Vitamin D and Treatment Regimens for Vitamin D Deficiency in HIV-Infected Adults

Vitamin D Level	Supplementation Regimen
>30 ng/mL	1000 IU/day vitamin D₃
21–29 ng/mL (insufficiency)	2000 IU/day vitamin D₃
15–19 ng/mL (deficiency)	Replacement: ergocalciferol 50 000 IU/week × 8 weeks (or equivalent of 6000 IU/day vitamin D₃)^a
	Maintenance: vitamin D₃ 2000 IU/day^b
<15 ng/mL (severe deficiency)	Replacement: Ergocalciferol 50 000 IU once or twice a week × 8–12 weeks (or equivalent of 6000 IU/day vitamin D₃)^a
	Maintenance: vitamin D₃ 2000 IU/day^b

Abbreviation: HIV, human immunodeficiency virus.

Consider a more aggressive replacement strategy if patient has secondary hyperparathyroidism, osteomalacia, malabsorption syndrome, or obesity or is taking medications that affect vitamin D metabolism.

Recheck 25-hydroxyvitamin D level after course of ergocalciferol, goal >30 ng/mL. Consider monitoring urinary calcium in patients with a history of nephrolithiasis and concurrent calcium supplemenation use.