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Survival of guinea pigs infected with Mycobacterium tuberculosis clinical isolates. Guinea pigs were infected by aerosol with average inoculum of 1 × 106 (range, 5.76–6.38 log) depositing 10–20 colony-forming units in the lungs. Guinea pig survival was plotted using the Kaplan-Meier method, and differences between curves were analyzed using the log-rank test. Results are from 2 representative experiments with 9 guinea pigs (A) and 13 guinea pigs (B) per group.
