TABLE 3.
Frequency of Major Morphologic Features
| Feature | No. (%) | |
|---|---|---|
| Lobular sinusoidal fibrosis | Prominent, extends beyond zone 3 | 12 (57) |
| Prominent, confined to zone 3 | 4 (19) | |
| Focal, extends beyond zone 3 | 2 (10) | |
| Focal, confined to zone 3 | 2 (10) | |
| Absent | 1 (5) | |
| Cannot assess | 1 | |
| Portal fibrosis (Scheuer criteria) | Stage 4 | 5 (24) |
| Stage 3 | 4 (19) | |
| Stage 2 | 5 (24) | |
| Stage 1 | 6 (29) | |
| Stage 0 | 1 (5) | |
| Cannot assess | 1 | |
| Bile plugs | Canalicular and ductal/ductular | 2 (9) |
| Canalicular only | 17 (77) | |
| Ductal/ductular only | 0 (0) | |
| Absent | 3 (14) | |
| Pseudorosette formation | Prominent | 11 (50) |
| Present | 9 (41) | |
| Absent | 2 (9) | |
| Lobular mononuclear leukocyte inflammation | Diffuse | 5 (23) |
| Focal | 8 (36) | |
| Rare | 7 (32) | |
| Absent | 2 (9) | |
| Portal inflammation | Generalized, moderate/marked | 4 (18) |
| Generalized, mild | 8 (36) | |
| Focal, mild | 8 (36) | |
| Absent | 2 (9) | |
| Hepatocellular necrosis | Many | 4 (18) |
| Few | 4 (18) | |
| Absent/rare | 14 (64) | |
| Giant cell transformation | Prominent | 5 (23) |
| Common | 1 (5) | |
| Present | 10 (45) | |
| Rare | 6 (27) | |
| Hepatocellular swelling | Prominent | 9 (41) |
| Present | 4 (18) | |
| Rare | 6 (27) | |
| Absent | 3 (14) |