Fig 5.

Impact of genetic deprivation of Hsp104 on biofilm architecture. (A) C. albicans biofilms were developed on highly adhesive round tissue culture coverslips, as a validation of subsequent experiments. Quantitative analyses of mature biofilms were documented by XTT reduction assay measured at 490 nm. Standard deviations were calculated from three independent experiments, each conducted with two coverslips per strain. (B) Pictures of mature biofilms formed on the surface of round tissue culture coverslips. (C) Scanning electron microscopy pictures of mature biofilms formed on the surface of round tissue culture coverslips. See text for details. Magnification, ×200.