Table 1.
Characteristics of patients on HAART and recent-infection classification according to EIA-RI measuring either IDE-V3 or IDE alonea
| Characteristic | Overall (n = 96) | No. of patients with indicated RI classification according to EIA-RI measuring: |
|||||
|---|---|---|---|---|---|---|---|
| IDE and V3 |
IDE only |
||||||
| Misclassified (n = 28) | Correctly classified (n = 68) | P value | Misclassified (n = 22) | Correctly classified (n = 74) | P value | ||
| Age (yr) | 50 (47–52) | 56 (52–59) | 48 (45–51) | NS | 56 (52–59) | 48 (45–51) | NS |
| Sex ratio (male/female) | 2.3 (67/29) | 6.0 (24/4) | 1.7 (43/25) | 0.029 | 4.5 (18/4) | 2.0 (49/25) | NS |
| CD4+ T-cell count: | |||||||
| At inclusion (cells/μl) | 417 (360–473) | 431 (316–545) | 399 (359–549) | NS | 418 (364–563) | 412 (398–530) | NS |
| At last follow-up (cells/μl) | 518 (461–574) | 467 (278–519) | 531 (504–635) | NS | 458 (375–672) | 531 (478–605) | NS |
| HAART duration (mo) | 138 (128–147) | 155 (140–171) | 123 (111–135) | 0.02 | 156 (133–171) | 123 (110–135) | 0.02 |
| Minimum duration of infection (mo) | 183 (163–193) | 181 (160–207) | 186 (159–197) | NS | 189 (157–211) | 178 (158–193) | NS |
| Strict viral suppression (mo) | 61 (56–69) | 80 (70–94) | 56 (51–65) | 0.005 | 95 (83–112) | 57 (51–66) | 0.002 |
| Virological suppression [no. (%)] | |||||||
| Viral rebound | 9 | 1 (11.1) | 8 (88.9) | 1 (11.1) | 8 (88.9) | ||
| Residual viremia | 45 | 14 (31.1) | 31 (68.9) | NS | 9 (20.0) | 36 (80.0) | NS |
| Strict viral suppressors | 42 | 13 (31.0) | 29 (69.0) | 12 (28.6) | 30 (71.4) | ||
| Virus subtype [no. (%)] | |||||||
| B | 73 (76.0) | 22 (30.1) | 51 (69.9) | 17 (23.3) | 56 (76.7) | ||
| Non-B | 19 (19.8) | 5 (26.3) | 14 (73.7) | NS | 4 (21.1) | 15 (78.9) | NS |
| Nontypeable | 4 (4.2) | 1 (25.0) | 3 (75.0) | 1 (25.0) | 3 (75.0) | ||