Table 2.
IL23R 1142 G → A allele and genotype frequencies in pulmonary tuberculosis cases and controlsa
| Allele or genotype | No. (%) of patients |
pTB cases vs controls |
Pmd vs controls |
Pad vs controls |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| pTB (n = 168) | Pmd (n = 123) | Pad (n = 45) | Controls (n = 150) | P | OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | |
| Allele | ||||||||||
| A | 113 (34) | 67 (27) | 46 (51) | 55 (18) | 10−5 | 2.26 (1.53–3.32) | 12 × 10−3 | 1.67 (1.09–2.55) | 10−8 | 4.66 (2.72–7.98) |
| G | 223 (66) | 179 (73) | 44 (49) | 245 (82) | ||||||
| Genotype | ||||||||||
| AA | 24 (14) | 9 (7) | 15 (33) | 8 (5) | 9 × 10−4 | 3.91 (1.57–10.05) | 0.25 | 1.78 (0.59–5.39) | 10−8 | 13.79 (4.47–44.04) |
| AG | 65 (39) | 49 (40) | 16 (36) | 39 (26) | 10−3 | 2.17 (1.29–3.67) | 9 × 10−3 | 1.99 (1.14–3.48) | 5 × 10−3 | 3.02 (1.25–7.3) |
| GG | 79 (47) | 65 (53) | 14 (31) | 103 (69) | ||||||
a
pTB, pulmonary tuberculosis; Pmd, pulmonary patients with minimal/moderate lung involvement; Pad, pulmonary patients with extensive lung involvement.