Fig 6.

In vitro suppressive activity of CD4⁺ CD25⁺ T cells in spleen 14 days after vaginal SIV challenge. On the day of SIV challenge or on days 7 and 14 postchallenge, the suppressive capacity of CD25⁺ CD4⁺ splenic T cells was assessed by comparing the proliferative capacity of mitogen-stimulated cells with or without CD25⁺ T cell depletion. A suppression index was calculated as described in Materials and Methods. P values were generated using Tukey's multiple comparison post hoc tests after a one-way ANOVA.