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. 2012 Sep;86(17):9361–9368. doi: 10.1128/JVI.01214-12

Table 3.

Virus titers in respiratory washes from infected cynomolgus macaquesa

Specimen and day Virus titer (log10 PFU/ml) in the indicated animals infected with:
Norway3568 virus
Norway3487 virus
367c 368e 369 370c 371c,e 372e 373c,e 374d 375c 376c
Nasal wash
    1 3.6 5.1 3.9 b 3.1 2.6
    3 1.8 1.9 1.8 1.9 1.6
    5 1.3 1. 8 2.5 1.6 NAf
    7 NA
    10 NA NA NA NA NA NA NA
    14 NA NA NA NA NA NA NA
Tracheal brush
    1 1. 8 4.2 5.3 3.0 2. 8 4.8 1.6 2.2 2.2
    3 1.3 3.6 1.3 4.0 3.4
    5 3.9 5.0 2.6 3.6 NA 2.2 2.7
    7 2.2 3.9 3.1 3.6 NA
    10 NA NA NA NA NA NA NA
    14 NA NA NA NA NA NA NA
BALg fluid
    1 4.4 4.1 6.5 4.1 4.5 4.6 6.7 6.3 6.6 5.3
    3 3.2 3.6 2.5 3.9 2.7 4.7 4.1 4.7 4.3 4.6
    5 1.6 2.6 1.3 3.6 2.2 5.8 4.3 NA 4.5 4.1
    7 NA
    10 NA NA NA NA NA NA NA
    14 NA NA NA NA NA NA NA
a

Cynomolgus macaques were infected with 6.7 × 107 PFU through multiple routes. Nasal wash and tracheal brush samples were collected every other day for virus titration.

b

—, virus not detected (detection limit, 1.3 log10 PFU/ml.

c

These animals were euthanized on day 7 postinfection for virologic and pathological analyses.

d

This animal died during the bronchoalveolar lavage procedure on day 3 postinfection.

e

These animals had Plasmodium spp. in their erythrocytes; however, their erythrocyte counts were normal.

f

NA, not applicable.

g

BAL, bronchoalveolar lavage.