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. 2012 Aug;194(16):4208–4225. doi: 10.1128/JB.00863-12

Fig 5.

Fig 5

Location of the putative G4FS in the T. pallidum subsp. pallidum (Nichols Gen strain) genome (19). (A) G4FS are mapped using the G-score (ranging from 29 to 63, shown in the outer ring) in the T. pallidum subsp. pallidum Nichols Gen strain. Except for the genomic region encompassed approximately between nt 550000 and 733330, G4FS appear to be evenly distributed throughout the genome. G4FS in proximity to the tprK DSs and tprK gene are indicated. (B) Two of the putative G4FS (yellow) located in the TP0131 3′-flanking region (TP0128-TP0127 intergenic spacer) in T. pallidum subspecies and T. paraluiscuniculi showing sequence diversity among these strains. For each putative G4FS the G-score is indicated below the sequences. The Street14 sequence is identical to the UW126 strain sequence, the Dal-1 sequence is identical to the Chicago strain sequence, and the CDC2 sequence is identical to the Gauthier sequence. (C) One of the putative G4FS (yellow) located in the TP0131 5′-flanking region (within the TP0136 ORF) in T. pallidum subspecies and T. paraluiscuniculi showing sequence diversity among these strains. The G4FS G-score is indicated below the sequence. The Street14 sequence is identical to the UW104 strain sequence, the Dal-1 sequence is identical to the Chicago strain sequence, and the CDC2 sequence is identical to the Gauthier sequence. (D) Putative G4FS located upstream of the tprK ORF in T. pallidum subspecies and T. paraluiscuniculi showing sequence diversity between the rabbit treponeme and the rest of the strains. Street14, Dal-1, and CDC2 sequences are identical to Nichols Gen sequences.