Fig 6.

Circular dichroism (CD) spectra of putative G4Fs in proximity to the tprK expression and donor sites. Most of the sequences fold into well-defined quadruplexes, with spectra compatible with G4 with all-parallel strand orientation for sequences 3 to 6. Sequence 1 failed to fold into a stable G4, despite its very elevated G-score. Sequence 2 folded into a structure that resembles a partly folded G4 with antiparallel strand orientation. Buffer alone was used as a negative control (data not plotted).