Table 3.

Genes downregulated by PatE, identified by use of microarray analysis

ORFa	Gene	Predicted function	Fold repressionb
Z3242		Hypothetical protein	−2.5
Z3796		Hypothetical protein	−2.2
Z3797	yfhO	KEGG database: cysteine desulfurase	−2.1
Z3907	grpE	Heat shock protein	−2.4
Z4769	yhgI	Hypothetical protein	−2.2
Z5105	espB	Type III secreted translocator	−2.4
Z5107	espA	Type III secreted protein	−2.4
Z5112	tir	Translocated intimin receptor protein	−2.0
Z5122	espZ	Type III secreted effector	−2.2
Z5137		Putative component of T3SS	−2.9
Z5138		Putative component of T3SS	−2.7
Z5182	ibpB	Heat shock protein	−5.7
Z5183	ibpA	Heat shock protein	−2.4
Z5204	tnaB	Low-affinity tryptophan transporter	−2.1
Z5232	atpA	ATP synthase, alpha subunit	−2.2
Z5233	atpH	ATP synthase, delta subunit	−2.0
Z5478	clpY	Heat shock protein, two-component protease	−2.7
Z5479	clpQ	Heat shock protein, two-component protease	−2.4

^aORF designations are given according to the EDL933 genome (accession no. AE005174.2).

^bDetermined by comparing the log₂ ratios of the transcript levels for strain EDL933(Δ3 Δstx1-2)/pJB11 to those for strain EDL933(Δ3 Δstx1-2)/pACYC184.