. 2012 Jul;80(7):2485–2492. doi: 10.1128/IAI.00145-12

Table 2.

The cheA₂^mut mutant fails to infect mice^a

Mouse strain	B. burgdorferi strain	No. of positive cultures/total no. of specimens examined				No. of mice infected/total no. of mice used
Mouse strain	B. burgdorferi strain	Ear	Skin	Joint	All sites	No. of mice infected/total no. of mice used
BALB/c	Wild type	4/4	4/4	4/4	12/12	4/4
	cheA₂^mut	0/4	0/4	0/4	0/12	0/4
	cheA₂^com	4/4	4/4	4/4	12/12	4/4
SCID	Wild type	3/3	3/3	3/3	9/9	3/3
	cheA₂^mut	0/3	0/3	0/3	0/9	0/3
	cheA₂^com	3/3	3/3	3/3	9/9	3/3

Groups of four BALB/c or three SCID mice were inoculated with 10⁵ spirochetes of the wild-type, cheA₂^mut, or cheA₂^com strain. Mice were sacrificed at 3 weeks postinoculation, and ear, skin, and tibiotarsal joint specimens were harvested for spirochete culture in BSK-II medium.