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Conformational-state model of AM-R1ab-R2ab. Different geometrical shapes filled with colors represent domains with an available high-resolution structure or a predicted homology model (R1ab). The dashed lines, blue and red, represent flexible linkers. The linker between AM and R1ab (L1) is highly flexible and adopts a broad range of compact as well as extended conformations. The linker between R1ab and R2ab (L2) is mostly extended but may also sample a few compact conformations.
