Main routes of pyruvate formation and conversion in P. freudenreichii during storage at 4°C and relevant for this study. Genes upregulated at 4°C are shown in black, and downregulated genes in gray. Thick black arrows emphasize the metabolic pathways that are favored at 4°C, and thin gray arrows the pathways that are downregulated at 4°C. ace, pyruvate dehydrogenase, E1 component; ald, alanine dehydrogenase; ldh, l-lactate dehydrogenase; ppdk, pyruvate phosphate dikinase; sdaA, l-serine dehydratase; sdh, succinate dehydrogenase; CoA, coenzyme A. Values of fold changes are shown in Table 1, Table 4, and Fig. 5.