Table 5.
Association between principal component analysis factor scores and colonization by AOM pathogensa
| AOM pathogen and factor | OR (95% CI) by antibiotic use in past 6 mo |
|
|---|---|---|
| Yes | No | |
| S. pneumoniae | ||
| Factor 1 | 1.03 (0.84, 2.02) | 0.49 (0.27, 0.89) |
| Factor 2 | 0.46 (0.23, 0.91) | 0.63 (0.40, 0.98) |
| Factor 3 | 1.33 (0.83, 2.15) | 1.45 (0.92, 2.27) |
| Factor 4 | 0.58 (0.36, 0.93) | 0.66 (0.45, 0.95) |
| H. influenzae | ||
| Factor 1 | 0.72 (0.44, 1.19) | 0.56 (0.30, 1.05) |
| Factor 2 | 0.43 (0.22, 0.86) | 0.49 (0.26, 0.93) |
| Factor 3 | 0.42 (0.16, 1.13) | 0.70 (0.41, 1.20) |
| Factor 4 | 0.25 (0.13, 0.50) | 0.40 (0.26, 0.93) |
| M. catarrhalis | ||
| Factor 1 | 0.70 (0.44, 1.11) | 0.66 (0.42, 1.03) |
| Factor 2 | 0.42 (0.22, 0.79) | 0.44 (0.24, 0.78) |
| Factor 3 | 1.90 (0.94, 3.86) | 1.23 (0.84, 1.80) |
| Factor 4 | 0.57 (0.36, 0.89) | 0.68 (0.47, 0.97) |
a
Odds ratios and 95% confidence intervals from logistic regression analyses. Separate analyses were performed for each AOM pathogen and antibiotic use group. Boldface indicates a significant result.