Table 3.
Survival rate of three month-old C3H mice immunized with NS1 or PBS
| Immunogen | Anti-NS1 IgG antibody titer rangea | No. of Survival mice/No. of Immunized mice (Survival rate) | Pb |
|---|---|---|---|
| NS1 |
0-12800 |
12/18 (66.7%) |
0.41 |
| NS1 |
0-2400 |
3/9 (33.3%) |
1 |
| NS1 |
2400-12800 |
9/9 (100%) |
0.008 |
| PBS | 0 | 4/9 (44.4%) |
a Two weeks before challenge, mouse sera were collected for anti-NS1 IgG antibody titration. The NS1-immunized group of mice (18 mice in total) was divided into two groups according to anti-NS1 IgG titers: one group with anti-NS1 IgG <2400 (9 mice) and one group with anti-NS1 IgG >2400 (9 mice).
bP value was obtained by log rank test when comparing the survival curve of each group with PBS group.