Table 5.
Survival rate of C3H mice passively immunized with anti-NS1 monoclonal antibodies
| MAbs | MAb dose (μg) | No. of survival mice/ No. of passive transfer mice (survival rate) | pa |
|---|---|---|---|
| 3E10 |
100 |
1/6 (16.7%) |
0.07 |
| |
500 |
1/6 (16.7%) |
0.05 |
| 4 C4 |
100 |
2/6 (33.3%) |
0.02 |
| |
500 |
2/6 (33.3%) |
0.15 |
| 7 C2 |
100 |
1/12 (8.3%) |
0.74 |
| |
500 |
1/6 (16.7%) |
0.02 |
| 7 H5 |
100 |
0/6 (0%) |
0.08 |
| |
500 |
0/6 (0%) |
0.02 |
| 8 F1 |
100 |
0/12 (0%) |
0.58 |
| |
500 |
0/6 (0%) |
0.02 |
| Anti-HIV | 100 | 0/6 (0%) |
aP value was obtained by log rank test when comparing the survival curve of each group of mice which received anti-NS1 MAb with anti-HIV group.